Patients should be switched to a different medication if pregnant or planning to become pregnant. There are few studies about the safety of Eliquis ® (apixaban) while pregnant. Is Eliquis ® safe to take during pregnancy? Patients on Eliquis ® (apixaban) don’t need to be as closely monitored as patients taking warfarin. Warfarin inhibits the protein that activates Vitamin K. They prevent platelets in the blood from clumping into a clot.Įliquis ® binds to a protein called Factor Xa, which stops it from building clots. They all slow clot formation in the body.Īnother similar class of drugs includes the antiplatelet agents, Plavix ® (clopidogrel), Effient ® (prasugrel), Brillinta ® (ticagrelor), and aspirin. This group also includes heparin, Coumadin ® (warfarin), Xarelto ® (rivaroxaban), and Pradaxa ® (dagibatran). How is Eliquis® different from other blood thinners?Įliquis ® (apixaban) belongs to a group of medications referred to as anticoagulants. Your blood is less likely to clot while taking Eliquis ®. Factor Xa plays a crucial role in the blood clotting mechanism when you get an injury by forming a mesh. What is apixaban’s mechanism of action?Įliquis ® (apixaban) is a direct factor Xa inhibitor that will binds to and inactivates factor Xa. They are given intravenously in a hospital and are used only when Eliquis® causes life-threatening or uncontrolled bleeding. Either can be used to reverse the effects of Eliquis ®. The reversal agents for Eliquis ® (apixaban) are Andexxa ® (andexanet alfa) and KCentra ® (prothrombin complex concentrate). It is best to avoid alcohol while taking Eliquis ®, but an occasional small drink is probably safe. The American Blood Clot Association recommends that anyone with a clotting disorder should use extreme caution when drinking. Finally, your risk of developing a blood clot increases after consuming more than two servings of alcohol per day. You are more likely to bleed internally after falling down while taking a blood thinner like Eliquis ®. If you drink too much alcohol, it may affect your balance. Alcohol may itself act as a blood thinner after just one or two drinks, by decreasing platelet clumping. Can I drink alcohol while on Eliquis ®?Īlcohol may increase the risk of bleeding in your stomach and intestines by irritating the tissue. These fruits prevent the breakdown of apixaban and may increase side effects. You should avoid grapefruit, grapefruit juice, marmalades, limes, and pomelos while you are taking Eliquis ®. You can take Eliquis ® (apixaban) with or without most foods. What foods should I avoid while taking Eliquis ®? You should also seek medical attention if you cough up or vomit blood, have unexpected joint pain or swelling, have severe headaches, or feel dizzy. You should call your doctor or seek medical help if you have unusual bleeding from the gums, frequent nosebleeds, menstrual bleeding that is heavier than normal, pink or brown urine, or red or black stools that resemble tar. While taking Eliquis ® you may bruise more easily and it may take longer for bleeding to stop. Eliquis can be used to treat blood clots in the veins of your legs or lungs, and reduce the risk of them occurring again. Eliquis ® is also used to reduce the risk of forming a blood clot in the legs and lungs of those who have just had hip or knee replacement surgery. Eliquis ® lowers your chance of having a stroke by helping to prevent clots from forming. People with atrial fibrillation (a type of irregular heartbeat) are at an increased risk of forming a blood clot in the heart, which can travel to the brain, causing a stroke, or to other parts of the body. Eliquis ® (apixaban) is an oral medication prescribed to reduce the risk of blood clotting and stroke.
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